Testosterone Therapy in Men With Prostate Cancer: Scientific and Ethical Considerations

Testosterone Therapy in Men With Prostate Cancer: Scientific and Ethical Considerations

Purpose Pertinent literature regarding the potential use of testosterone therapy in men with prostate cancer is reviewed and synthesized.

Materials and Methods A literature search was performed of English language publications on testosterone administration in men with a known history of prostate cancer and investigation of the effects of androgen concentrations on prostate parameters, especially prostate specific antigen.

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Should Testosterone Be Tested Under Fasted Conditions?

Should Testosterone Be Tested Under Fasted Conditions?

CONCLUSION: "Until the mechanism behind this effect has been explored, we suggest that assessment of S-T for diagnostic purposes should be collected in the morning after an overnight fasting."

Andrologia. 2012 Dec;44(6):405-10. doi: 10.1111/j.1439-0272.2012.01296.x. Epub 2012 Apr 23.

S-testosterone decrease after a mixed meal in healthy men independent of SHBG and gonadotrophin levels.

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Testosterone May Benefit Seniors with Chronic Heart Failure

Testosterone may benefit seniors with chronic HF

The exercise plus testosterone group experienced improvements from baseline in peak oxygen uptake (P<.01), Beck Depression Inventory (P<.05), leg strength (P<.05) and several Medical Outcomes Study Short-Form quality of life domains (P<.05). These improvements were generally not observed in the exercise plus placebo group, according to the abstract. Similar improvements in shuttle walk test (18% vs. 19%), body mass (–1.3 kg vs. –1 kg) and hand grip strength (2.1 kg vs. 2.5 kg) from baseline to 12 weeks were recorded in both groups.

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Testosterone Therapy Decreases Liver Fat

Testosterone Therapy Decreases Liver Fat

Testosterone administration in older men with mobility limitation and low testosterone levels was not associated with a reduction in hepatic fat.

More on fatty liver and its consequences:

Nonalcoholic fatty liver disease is now the most common cause of chronic liver disease in the U.S. Some people with excess fat in the liver simply have what's called a fatty liver. Although this is not normal, it is not serious if it doesn't lead to inflammation or damage.

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  • Outcomes of Long-Term Testosterone Replacement in Older Hypogonadal Males: A Retrospective Analysis +

    Comparison of self-assessment of libido at the 2 year point showed a dramatic improvement in the testosterone group compared to Read More
  • Testosterone Therapy Decreases Liver Fat +

    Testosterone administration in older men with mobility limitation and low testosterone levels was not associated with a reduction in hepatic Read More
  • Testosterone May Benefit Seniors with Chronic Heart Failure +

    The exercise plus testosterone group experienced improvements from baseline in peak oxygen uptake (P Read More
  • Should Testosterone Be Tested Under Fasted Conditions? +

    CONCLUSION: "Until the mechanism behind this effect has been explored, we suggest that assessment of S-T for diagnostic purposes should Read More
  • Testosterone Therapy in Men With Prostate Cancer: Scientific and Ethical Considerations +

    Purpose Pertinent literature regarding the potential use of testosterone therapy in men with prostate cancer is reviewed and synthesized. Materials Read More
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